| Head southwest on Карађорђа Петровића | 600 m |
| Enter the traffic circle and take the 2nd exit onto 41 | 40 m |
| Exit the traffic circle onto 41 | 700 m |
| Take the ramp on the right towards Ниш / Niš | 450 m |
| Go straight | 300 m |
| Merge left onto A1 | 100 km |
| Keep left onto A1 | 80 km |
| Continue onto Θεσσαλονίκης - Ευζώνων (ΕΟ1) | 500 m |
| Take the ramp on the left | 200 m |
| Merge right onto Θεσσαλονίκης - Ευζώνων (ΕΟ1) | 1 km |
| Continue onto Αθήνα - Θεσσαλονίκη - Εύζωνοι (Α1) | 60 km |
| Keep right towards Α1: Κατερίνη | 1 km |
| Merge left onto Εγνατία Οδός (Α2) | 10 km |
| Continue onto Ηγουμενίτσα - Θεσσαλονίκη - Κήποι Έβρου (Α1) | 150 m |
| Take exit 17 towards Α2: Κοζανη | 400 m |
| Continue onto Εγνατία Οδός (Α2) | 200 km |
| Take the ramp towards ΕΟ5: Αθήνα | 250 m |
| Enter Αντίρριο - Ιωάννινα and take the 3rd exit onto Αντίρριο - Ιωάννινα (ΕΟ5) | 200 m |
| Exit the traffic circle onto Αντίρριο - Ιωάννινα (ΕΟ5) | 700 m |
| Enter the traffic circle and take the 1st exit onto Αντίρριο - Ιωάννινα (ΕΟ5) | 40 m |
| Exit the traffic circle onto Αντίρριο - Ιωάννινα (ΕΟ5) | 150 m |
| Enter the traffic circle and take the 1st exit onto Αντίρριο - Ιωάννινα (ΕΟ5) | 35 m |
| Exit the traffic circle onto Αντίρριο - Ιωάννινα (ΕΟ5) | 3 km |
| Enter the traffic circle and take the 2nd exit onto Αντίρριο - Ιωάννινα (ΕΟ5) | 35 m |
| Exit the traffic circle onto Αντίρριο - Ιωάννινα (ΕΟ5) | 2.5 km |
| Enter the traffic circle and take the 1st exit | 20 m |
| Exit the traffic circle | 450 m |
| Keep left towards A5: Πάτρα | 900 m |
| Merge left onto Ιόνια Οδός (Α5) | 100 km |
| Take the ramp towards ΕΟ5: Αγρίνιο | 300 m |
| Make a sharp right onto Αντιρρίου - Ιωαννίνων (ΕΟ5) | 15 km |
| Turn left | 150 m |
| Turn right onto Αγρίνιο - Γέφυρα Ματσουκίου | 2 km |
| Continue onto Αγίου Κωνσταντίνου | 1.5 km |
| Keep right onto Ηρώων Πολυτεχνείου | 900 m |
| Go straight onto Δαγκλή | 200 m |
| Turn left onto Αναστασιάδη | 100 m |
| You have arrived at your destination, straight ahead | 0 m |
