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Sereflikochisar – Nizip
Ankara - Adana Yolu, Adana-Şanlıurfa Otoyolu
592.2 km, 6 h 20 min
| Head southeast | 50 m | |
| Turn left | 90 m | |
| Turn right | 100 m | |
| Turn right onto 06-30 | 90 m | |
| Turn left onto E90 Karayolu Blv. (D750) | 2.5 km | |
| Enter the traffic circle and take the 2nd exit onto E90 Karayolu Blv. (D750) | 10 m | |
| Exit the traffic circle onto E90 Karayolu Blv. (D750) | 800 m | |
| Exit the traffic circle onto E90 Karayolu Blv. (D750) | 20 km | |
| Continue onto Ankara-Adana yolu (D750) | 25 km | |
| Continue onto Ankara - Adana Yolu (D750) | 25 km | |
| Turn right onto 95. Cadde | 1 km | |
| Continue onto 101. Cadde | 900 m | |
| Enter the traffic circle and take the 2nd exit onto 101. Cadde | 25 m | |
| Exit the traffic circle onto 101. Cadde | 900 m | |
| Take the ramp on the right | 200 m | |
| Merge left onto Ankara - Adana Yolu (D300) | 1.5 km | |
| Keep left onto Ankara - Adana Yolu (D750) | 3.5 km | |
| Enter the traffic circle and take the 1st exit onto Ankara - Adana Yolu (D750) | 15 m | |
| Exit the traffic circle onto Ankara - Adana Yolu (D750) | 7 km | |
| Exit the traffic circle onto Ankara - Adana Yolu (D750) | 4.5 km | |
| Continue straight to stay on Ankara - Adana Yolu (D750) | 25 km | |
| Keep right onto Ankara - Adana Yolu (D750) | 25 km | |
| Keep left onto Ankara - Adana Yolu (D750) | 800 m | |
| Continue onto Ankara-Adana yolu (D750) | 20 km | |
| Take the ramp onto Ereğli Köprülü Kavşağı | 800 m | |
| Merge left onto Ereğli Köprüsü (O-21A) | 60 m | |
| Continue onto Pozantı - Afyonkarahisar Otoyolu (O-21A) | 30 km | |
| Keep right onto Eminlik Kavşağı (O-21A) | 1.5 km | |
| Merge left onto Pozantı - Niğde Otoyolu (O-21) | 15 km | |
| Continue onto Kırkgeçit-1 Viyadüğü (O-21) | 250 m | |
| Continue onto Ankara-Tarsus Otoyolu (O-21) | 150 m | |
| Continue onto Kırkgeçit-1 Tüneli (O-21) | 900 m | |
| Continue onto Pozantı - Niğde Otoyolu (O-21) | 600 m | |
| Continue onto Kırkgeçit-2 Viyadüğü (O-21) | 300 m | |
| Continue onto Kırkgeçit-2 Tüneli (O-21) | 550 m | |
| Continue onto Pozantı - Niğde Otoyolu (O-21) | 500 m | |
| Continue onto Kırkgeçit-3 Tüneli (O-21) | 300 m | |
| Continue onto Kırkgeçit-4 Viyadüğü (O-21) | 300 m | |
| Continue onto Pozantı - Niğde Otoyolu (O-21) | 80 km | |
| Continue onto K28 Tarsus Doğu Kavşağı (O-21) | 500 m | |
| Take the ramp on the left towards O-51 | 2.5 km | |
| Merge left onto Adana-Erdemli Otoyolu (O-51) | 10 km | |
| Go straight onto Adana-Erdemli Otoyolu (O-51) | 100 m | |
| Keep left onto Adana-Erdemli Otoyolu (O-51) | 400 m | |
| Merge right onto Adana-Erdemli Otoyolu (O-51) | 20 km | |
| Continue onto Fehmi Özeltürkay Tüneli (O-51) | 300 m | |
| Continue onto Adana-Şanlıurfa Otoyolu (O-52) | 40 km | |
| Go straight onto O-52 | 500 m | |
| Merge left onto Adana-Şanlıurfa Otoyolu (O-52) | 20 km | |
| Keep left onto Adana-Şanlıurfa Otoyolu (O-52) | 70 km | |
| Continue onto Kızlaç Tüneli (O-52) | 3 km | |
| Continue onto Adana-Şanlıurfa Otoyolu (O-52) | 100 km | |
| Take the ramp | 1.5 km | |
| Keep right at the fork | 800 m | |
| Continue onto Mustafa Kökmen Bulvarı | 1.5 km | |
| Enter the traffic circle and take the 2nd exit | 45 m | |
| Exit the traffic circle | 100 m | |
| Make a slight right | 150 m | |
| You have arrived at your destination, on the left | 0 m |
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