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Regina – St. Louis
I 29; US 81, I 29
2183.9 km, 25 h
| Head north on Albert Street | 30 m | |
| Make a U-turn and continue on Albert Street | 6 km | |
| Continue onto CanAm Highway (6) | 100 km | |
| Continue onto Highway 39 (39) | 80 km | |
| Turn left onto Highway 39 (39) | 15 km | |
| Turn left to stay on Highway 39 (39) | 35 km | |
| Keep left at the fork | 20 m | |
| Take the ramp | 150 m | |
| Merge left onto US 52 | 10 km | |
| Turn left onto United States Highway 52 (US 52) | 45 km | |
| Continue onto 506th Street Northwest (US 52) | 35 km | |
| Continue onto 2nd Avenue (US 52) | 60 km | |
| Take the ramp towards US 52 East: Jamestown | 600 m | |
| Turn right onto US 52 | 100 km | |
| Continue onto United State Highway 52 (US 52) | 450 m | |
| Continue onto 23rd Street Northeast (US 52) | 45 km | |
| Turn left onto United States Highway 52 (US 52) | 35 km | |
| Turn right onto 19th Avenue (1605) | 1.5 km | |
| Turn left onto 7th Street South | 1.5 km | |
| Turn right onto 4th Avenue South (US 52) | 60 km | |
| Turn right onto US 52 Bypass (US 52 Truck) | 4.5 km | |
| Continue onto 81st Street Southeast (US 52 Truck) | 1.5 km | |
| Take the ramp on the left towards Fargo | 15 km | |
| Continue onto I 94 | 150 km | |
| Take the ramp towards I 29 South: Sioux Falls | 700 m | |
| Merge left onto I 29 | 700 km | |
| Keep right onto I 29 | 250 km | |
| Merge right onto I 29 | 3.5 km | |
| Keep right towards I 435 East: Saint Louis | 45 km | |
| Keep right towards I 70: Saint Louis | 450 m | |
| Keep left towards I 70 East: Saint Louis | 2 km | |
| Keep left towards I 70 East: Saint Louis | 150 m | |
| Merge left onto George Brett Super Highway (I 70) | 700 m | |
| Continue onto Truman/Eisenhower Presidential Highway (I 70) | 4.5 km | |
| Continue onto Clifton J. Scott Memorial Highway (I 70) | 3 km | |
| Continue onto Truman/Eisenhower Presidential Highway (I 70) | 4 km | |
| Continue onto Dwight D. Eisenhower Highway (I 70) | 80 km | |
| Continue onto U.S. Submarine Veterans' Memorial Highway (I 70) | 50 km | |
| Keep left onto U.S. Submarine Veterans' Memorial Highway (I 70) | 35 km | |
| Continue onto Dwight D. Eisenhower Highway (I 70) | 3 km | |
| Continue onto Highway Patrol Sgt. Benjamin Booth Memorial Highway (I 70) | 2.5 km | |
| Continue onto Sheriff Roger I. Wilson Memorial Highway (I 70) | 3 km | |
| Continue onto Dwight D. Eisenhower Highway (I 70) | 150 km | |
| Take exit 210A towards I 64 East: Chesterfield | 500 m | |
| Merge left onto Avenue of the Saints (I 64) | 45 km | |
| Continue onto Daniel Boone Expressway (I 64) | 9 km | |
| Continue onto Jack Buck Memorial Highway (I 64) | 10 km | |
| Take exit 39B on the left towards 11th Street | 300 m | |
| Continue onto South 11th Street | 350 m | |
| Turn left onto Market Street | 90 m | |
| You have arrived at your destination, on the left | 0 m |
I 94, Avenue of the Saints
2095.9 km, 25 h
| Head north on Albert Street | 30 m | |
| Make a U-turn and continue on Albert Street | 6 km | |
| Continue onto CanAm Highway (6) | 100 km | |
| Continue onto Highway 39 (39) | 80 km | |
| Turn left onto Highway 39 (39) | 15 km | |
| Turn left to stay on Highway 39 (39) | 35 km | |
| Keep left at the fork | 20 m | |
| Take the ramp | 150 m | |
| Merge left onto US 52 | 10 km | |
| Turn left onto United States Highway 52 (US 52) | 45 km | |
| Continue onto 506th Street Northwest (US 52) | 35 km | |
| Continue onto 2nd Avenue (US 52) | 60 km | |
| Take the ramp towards US 52 East: Jamestown | 600 m | |
| Turn right onto US 52 | 100 km | |
| Continue onto United State Highway 52 (US 52) | 450 m | |
| Continue onto 23rd Street Northeast (US 52) | 45 km | |
| Turn left onto United States Highway 52 (US 52) | 35 km | |
| Turn right onto 19th Avenue (1605) | 1.5 km | |
| Turn left onto 7th Street South | 1.5 km | |
| Turn right onto 4th Avenue South (US 52) | 60 km | |
| Turn right onto US 52 Bypass (US 52 Truck) | 4.5 km | |
| Continue onto 81st Street Southeast (US 52 Truck) | 1.5 km | |
| Take the ramp on the left towards Fargo | 15 km | |
| Continue onto I 94 | 300 km | |
| Continue onto I 94 | 200 km | |
| Take exit 216 towards I 494 South | 700 m | |
| Continue onto I 494 | 35 km | |
| Take the ramp | 100 m | |
| Continue onto I 494 | 200 m | |
| Take exit 5B towards I 35W South: Albert Lea | 550 m | |
| Merge left onto I 35W | 200 km | |
| Take the ramp towards US 18 East: Mason City | 700 m | |
| Keep right towards US 18 East: Mason City | 150 km | |
| Take the ramp towards US 218 south: Waterloo | 100 m | |
| Continue towards US 218 south: Waterloo | 500 m | |
| Merge left onto Leo P Rooff Expressway (US 218) | 10 km | |
| Continue onto Washington Street (US 218) | 4 km | |
| Keep right towards I-380 south: Cedar Rapids | 10 km | |
| Keep right towards I 380 South: Cedar Rapids | 200 km | |
| Keep left onto Avenue of the Saints (US 218) | 150 km | |
| Continue towards US 61 South: Hannibal | 6 km | |
| Turn right onto MO W | 2.5 km | |
| Turn right onto Veterans Road | 5 km | |
| Turn left onto County Road 422 | 90 m | |
| Continue onto Paris Gravel Road | 800 m | |
| Take the ramp on the right | 35 m | |
| Merge left onto Avenue of the Saints (US 61) | 150 km | |
| Continue onto Daniel Boone Expressway (I 64) | 9 km | |
| Continue onto Jack Buck Memorial Highway (I 64) | 10 km | |
| Take exit 39B on the left towards 11th Street | 300 m | |
| Continue onto South 11th Street | 350 m | |
| Turn left onto Market Street | 90 m | |
| You have arrived at your destination, on the left | 0 m |
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