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Karamursel – Edessa
Tekirdağ - İpsala Yolu, Εγνατία Οδός
762.3 km, 8 h 58 min
| Head south on 2125. Sokak | 25 m | |
| Turn right onto Amiral Caddesi | 200 m | |
| Go straight | 150 m | |
| Merge left onto D130-1 YALOVA YOLU (D130-1) | 3.5 km | |
| Enter the traffic circle and take the 2nd exit onto D130-1 YALOVA YOLU (D130-1) | 20 m | |
| Exit the traffic circle onto D130-1 YALOVA YOLU (D130-1) | 1 km | |
| Continue onto D130-2 YALOVA YOLU (D130-2) | 1.5 km | |
| Exit the traffic circle onto D130-2 YALOVA YOLU (D130-2) | 5.5 km | |
| Continue onto D-130-2 YALOVA YOLU (D-130-2) | 250 m | |
| Take exit K-2-1 towards O5: Osmangazi Köprüsü | 1 km | |
| Continue towards E881: Osmangazi Köprüsü | 300 m | |
| Keep left towards O-5: Osmangazi Köprüsü | 1.5 km | |
| Merge left towards O-5: Gebze | 10 km | |
| Keep left towards O-4: İstanbul | 400 m | |
| Keep left towards O4: İstanbul | 1.5 km | |
| Merge left towards O-4 | 40 km | |
| Take the ramp onto İMES Köprülü Kavşağı | 400 m | |
| Keep left towards K.Bakkalköy | 350 m | |
| Keep left onto İMES Köprülü Kavşağı | 500 m | |
| Merge left onto Anadolu Otoyolu (O-4) | 1.5 km | |
| Take the ramp towards Ümraniye | 2 km | |
| Continue onto 2. Çevre Yolu (O-2) | 4 km | |
| Keep left onto 2. Çevre Yolu (O-2) | 30 km | |
| Continue towards O-2: Avcılar | 400 m | |
| Continue towards O-2: Avcılar | 150 m | |
| Take exit K-20 towards Güneşli | 250 m | |
| Keep left towards Güneşli | 350 m | |
| Merge left towards İSTOÇ | 60 km | |
| Take exit K-1 towards D-110: Marmara Ceza İnfaz Kurumları | 500 m | |
| Keep left towards D-110: Marmara Ceza İnfaz Kurumları | 2 km | |
| Merge left onto Kınalı-Balıkesir Otoyolu (O-6) | 2.5 km | |
| Keep left onto Silivri Otoyol Bağlantı Yolu | 4.5 km | |
| Merge right onto D-100 | 500 m | |
| Keep left onto D-110 | 35 km | |
| Keep right onto D-110 | 15 km | |
| Keep right onto İstanbul Bulvarı (D-110) | 2 km | |
| Continue onto Tekirdağ Çevreyolu (D-110) | 350 m | |
| Continue towards D-110: Malkara | 6 km | |
| Continue towards D-110: Malkara | 6 km | |
| Continue onto İsmet İnönü Bulvarı (D-110) | 40 km | |
| Continue onto Tekirdağ - İpsala Yolu (D-110) | 35 km | |
| Enter Doktor Sadık Ahmet Köprülü Kavşağı and take the 2nd exit onto Tekirdağ - İpsala Yolu (D-110) | 70 m | |
| Exit the traffic circle onto Tekirdağ - İpsala Yolu (D-110) | 25 km | |
| Take the ramp onto D-110 | 1.5 km | |
| Continue onto ΕΟ2 | 1 km | |
| Continue onto Εγνατία Οδός (Α2) | 350 km | |
| Take the ramp towards Α2: Αθηνα | 9 km | |
| Take the ramp towards EO2: Έδεσσα | 300 m | |
| Turn right onto Φλώρινας - Θεσσαλονίκης (ΕΟ2) | 5 km | |
| Continue onto Θεσσαλονίκη - Έδεσσα (ΕΟ2) | 500 m | |
| Continue onto Φλώρινας - Θεσσαλονίκης (ΕΟ2) | 15 km | |
| Continue onto Θεσσαλονίκης - Βέροιας (ΕΟ1) | 2 km | |
| Continue onto Εθνικής Αντιστάσεως (ΕΟ1) | 2 km | |
| Continue onto Θεσσαλονίκης - Έδεσσας (ΕΟ2) | 900 m | |
| Turn left onto Συνδετήρια Οδός | 250 m | |
| Continue onto Φλώρινας - Θεσσαλονίκης | 10 km | |
| Take the ramp | 35 m | |
| Merge left onto Συνδετήρια οδός | 900 m | |
| Turn left onto Θεσσαλονίκης - Έδεσσας (ΕΟ2) | 5 km | |
| Continue onto Εγνατίας (ΕΟ2) | 1.5 km | |
| Continue onto Θεσσαλονίκης - Έδεσσας (ΕΟ2) | 3 km | |
| Turn left onto Συνδετήρια Οδός | 100 m | |
| Continue slightly right onto Φλώρινας - Θεσσαλονίκης | 20 km | |
| Continue onto Συνδετήρια Οδός | 200 m | |
| Turn left to stay on Συνδετήρια Οδός | 550 m | |
| Continue onto Μεγάλου Αλεξάνδρου | 350 m | |
| Continue slightly right onto Θεσσαλονίκης - Έδεσσας (ΕΟ2) | 10 km | |
| Turn right | 500 m | |
| Turn left onto Θεσσαλονίκης - Έδεσσας (ΕΟ2) | 20 m | |
| Turn right onto Ντερέ | 350 m | |
| Turn left onto Στρατού | 45 m | |
| Turn right | 25 m | |
| Turn right | 90 m | |
| Make a slight left onto Δράμας | 100 m | |
| Turn right onto Καποδίστρια | 100 m | |
| Turn left onto Παλαιολόγου | 200 m | |
| You have arrived at your destination, on the right | 0 m |
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