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Amasya – Neapoli
İstanbul-Samsun yolu, Εγνατία Οδός
1270.0 km, 14 h 12 min
| Head north on Şehit Ahmet Özsoy Caddesi | 600 m | |
| Turn left onto Zübeyde Hanım Caddesi | 1.5 km | |
| Take the ramp | 150 m | |
| Make a slight left onto Recep Tayyip Erdoğan Bulvarı (D100) | 4.5 km | |
| Continue onto Fatih Sultan Mehmet Caddesi (D100) | 4 km | |
| Make a slight left onto D100 | 15 km | |
| Merge left onto Suluova Otogar Kavşağı (D100) | 35 m | |
| Keep right onto İstiklal Caddesi (D100) | 20 km | |
| Keep left onto Merzifon-Osmancık yolu (D100) | 20 km | |
| Continue onto İstanbul-Samsun yolu (D100) | 15 km | |
| Keep right onto D100 | 20 km | |
| Enter the traffic circle and take the 2nd exit onto İstanbul-Samsun yolu (D100) | 20 m | |
| Exit the traffic circle onto İstanbul-Samsun yolu (D100) | 2.5 km | |
| Enter İstanbul - Samsun Yolu and take the 2nd exit onto Ömer Derindere Bulvarı (D100) | 20 m | |
| Exit the traffic circle onto Ömer Derindere Bulvarı (D100) | 200 km | |
| Continue onto İstanbul - Samsun Yolu (D100) | 15 km | |
| Continue onto İstanbul-Samsun yolu (D100) | 40 km | |
| Continue onto İstanbul-Samsun Yolu (D-100) | 7 km | |
| Continue onto D100 | 200 m | |
| Enter the traffic circle and take the 1st exit onto D100 | 25 m | |
| Exit the traffic circle onto D100 | 7 km | |
| Keep right onto D100 | 5 km | |
| Continue onto D-100 | 5.5 km | |
| Turn left | 600 m | |
| Keep right onto Yeniçağa Kavşağı | 800 m | |
| Merge left onto Anadolu Otoyolu (O-4) | 150 km | |
| Keep right onto Kuzey Marmara Otoyolu (O-7) | 100 km | |
| Keep left onto Kuzey Marmara Otoyolu (O-7) | 30 km | |
| Continue onto Viyadük-29 (O-7) | 600 m | |
| Continue onto Kuzey Marmara Otoyolu (O-7) | 3 km | |
| Keep left onto Kuzey Marmara Otoyolu (O-7) | 100 km | |
| Continue onto Kınalı-Balıkesir Otoyolu (O-6) | 4.5 km | |
| Keep left onto Silivri Otoyol Bağlantı Yolu | 4.5 km | |
| Merge right onto D-100 | 500 m | |
| Keep left onto D-110 | 35 km | |
| Keep right onto D-110 | 15 km | |
| Keep right onto İstanbul Bulvarı (D-110) | 2 km | |
| Continue onto Tekirdağ Çevreyolu (D-110) | 350 m | |
| Continue towards D-110: Malkara | 6 km | |
| Continue towards D-110: Malkara | 6 km | |
| Continue onto İsmet İnönü Bulvarı (D-110) | 40 km | |
| Continue onto Tekirdağ - İpsala Yolu (D-110) | 35 km | |
| Enter Doktor Sadık Ahmet Köprülü Kavşağı and take the 2nd exit onto Tekirdağ - İpsala Yolu (D-110) | 70 m | |
| Exit the traffic circle onto Tekirdağ - İpsala Yolu (D-110) | 25 km | |
| Take the ramp onto D-110 | 1.5 km | |
| Continue onto ΕΟ2 | 1 km | |
| Continue onto Εγνατία Οδός (Α2) | 350 km | |
| Continue onto Θεσσαλονίκης - Καβάλας (ΕΟ2) | 1.5 km | |
| Continue onto Λαγκαδά (ΕΟ2) | 1 km | |
| Continue onto Μίκη Θεοδωράκη (ΕΟ2) | 2 km | |
| Turn left onto Δαβάκη | 300 m | |
| Turn right onto Διδυμοτείχου | 55 m | |
| Turn left onto Ζάκα | 150 m | |
| Turn right onto Κεσσάνης | 400 m | |
| Turn right onto Μπινιώρη | 20 m | |
| You have arrived at your destination, on the right | 0 m |
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